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ToF-SIMS-analysis of complex surface modifications
QCM-D based characterization of lipid-based sensor templates developed for SPR analysis
Preparation, characterization and immune system activation in blood by new conducting electrode materials in pacemaker applications
Soft- and bone tissue reactions on loaded microimplants with different surface modifications
Interaction of antithrombin with different types of heparin surfaces with implications for cellular interactions
Soft- and bone tissue reactions on loaded microimplants with different surface modifications  
Biocompatible Materials » Project survey » Projects in cooperation with industries » Soft- and bone tissue reactions on loaded microimplants with different surface modifications
Project description
 
The company which submitted the application, Osspol AB, is in its start-up phase and is not yet on the market with its product, a new dental implant system.

The purpose with the project was to explore the knowledge that was built up in the project “Optimal surface topography for bone anchored implants”, where different titanium surfaces were investigated in in vivo studies on rabbits, and under the restrictions that the studied surfaces should be possible to manufacture in a large-scale production to reasonable cost.

In this project, these investigations were extended to comprise human tissue, using microimplants that were inserted close to regular implants on patients undergoing treatment for edentulism. This is an established technique, but was here modified in the sense that the microimplants had a part penetrating the mucosa, and were loaded via the patients own prostheses. The surfaces studied were based on the knowledge about surface structures built up in the project "Optimal surface topography...", and on a recently developed technique to dope the surface oxide with ions expected to enhance the healing process.

Lennart Carlsson, CEO, says: “It is extremely valuable to have direct access to the academic research, especially for smaller companies where the need for expertise and resources often vastly exceeds resources within the company. The best way to gain knowledge for us is to run concrete projects together with academic research groups. This particular project is of considerable importance for us, since it focuses on properties of the implant that are crucial for its performance”.

www.fy.chalmers.se
www.chalmers.se
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  SSF research programme: Biocompatible Materials
Fysik och teknisk fysik
Chalmers tekniska högskola och Göteborgs universitet
412 96  Göteborg
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