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ToF-SIMS-analysis of complex surface modifications
QCM-D based characterization of lipid-based sensor templates developed for SPR analysis
Preparation, characterization and immune system activation in blood by new conducting electrode materials in pacemaker applications
Soft- and bone tissue reactions on loaded microimplants with different surface modifications
Interaction of antithrombin with different types of heparin surfaces with implications for cellular interactions
QCM-D based characterization of lipid-based sensor templates developed for SPR analysis  
Biocompatible Materials » Project survey » Projects in cooperation with industries » QCM-D based characterization of lipid-based sensor templates developed for SPR analysis
Project description
 
The company which submitted the application, Biacore AB, is the world leader in the detection and monitoring of biomolecular binding using surface plasmon resonance (SPR) technology. The company develops, manufactures and markets advanced bio-analytical systems that provide real-time quantitative data on binding interactions between biomolecules. The project was based on using the QCM-D technique, at Dept. of Chemical Physics (Dr. F. Höök), and at Biacore, to study vaarious aspects of the Biacore chips.

Stefan Löfås, VP, Chief Scientific Officer, says: “The Biacore sensor surfaces (or sensor chips) are the core components in the commercial Biacore instrument systems and thus of central importance for the technology. The funding of this project has facilitated the research together with the Department of Applied Physics at Chalmers/GU which had probably not been possible to do otherwise. The most significant benefits for Biacore in this collaborative project are as follows:
- Crucial funding for a bilateral focused project with clear objectives and agreed commitment from both partners.
- Access to an interesting complementary surface characterisation tool.
- Access to world class experts (its inventors) for the experiments and interpretations of the data.
- Extension of the scientific network.
- Increased knowledge and competence rising among Biacore employees for characterisation methods of importance.
- Possibility to interact and transfer technology know-how that otherwise had been impossible or a tedious and costly process if done separately.
- Results of great interest for both partners, which also will be beneficial for Biacore in the future development of the core surface technology.”


www.fy.chalmers.se
www.chalmers.se
www.gu.se
  SSF research programme: Biocompatible Materials
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Chalmers tekniska högskola och Göteborgs universitet
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