| Project survey
The programme has been a mix of large projects, running over most of the
programme time, and smaller and exploratory projects running over a more
limited time. For an overview see the table below.
The Biocompatible Materials programme was (at least for the first 3/4 of the
time), centred around five
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(i) Optimal surface topography for bone anchored implants
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(ii) Tribology of articulating joints
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(iii) Screening of tissue integrated materials (STIM)
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(iv) A systematic approach to improve blood compatibility of
biomaterials for cardiovascular applications
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(v) Time and functionally programmed surfaces (TFPS)
These projects have been running over most of the programme lifetime, apart
from STIM, that was started in 1999. In addition, six exploratory projects
have complemented the programme (most of these projects have been run over
only part of the total programme time):
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(vi) Investigations of mussel adhesive proteins for application
in biomaterial research and in clinic (co-financed with another SSF
programme: MASTEC)
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(vii) Supported biomembranes (co-financed with the SSF-funded
Biomaterials consortium until 2000)
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(viii) Neural stem cell culture model
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(ix) Bone cell culture model
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(x) Lotus-leaf effect
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(xi) Theoretical modelling and simulations
Also, as a result of the successive strategic redirection of the programme,
triggered by the rapid scientific development and by the efforts of the Board
and the PD to expand the research base to also comprise industries and
academic research groups outside the programme, the projects listed below
have been funded during the last 1-2 years of the programme. The basic idea
here was to bring in new groups from academia or industry to broaden the
network established during the first years of the programme, and thereby
create opportunities for new collaborations and possibly also for new funding.
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(xii) Cell-force sensor
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(xiii) Neural stem cell differentiation under electrical stimulation
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(xiv) Probing interactions between phospholipids and phosphatidyl
choline containing polymers
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(xv) Mucin modification of biomaterials: Biopolymer adsorption
kinetics and surface arrangement
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(xvi) ToF-SIMS-analysis of complex surface modifications
(together with Carmeda)
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(xvii) QCM-D based characterization of lipid-based sensor templates
developed for SPR analysis (together with Biacore)
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(xviii) Preparation, characterization and immune system activation
in blood by new conducting electrode materials in pacemaker
applications (together with St Jude Medical)
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(xix) Soft- and bone tissue reactions on loaded microimplants
with different surface modifications (together with Osspol)
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(xx) Interaction of antithrombin with different types of heparin
surfaces with impli-cations for cellullar interactions (together with
Corline)
You can reach more information about the above projects via the links to
the left.
In the Table below, a schematic representation of the funded projects over
time is shown. The date of first and last payment gives the start and end
dates for the larger projects. For the smaller projects, the date of decision
by the board is used as the start, while the end is given by either
anticipated or reported end dates.
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